Blessed with a great New York City loft, a thriving career and a no-strings relationship with a married man, Missy (Cynthia Nixon) has little interest in getting tied down romantically. That changes, however, when she meets Brat (Timothy Olyphant) -- who'd be the perfect guy if he weren't dating her gay best friend, Spaz (Andy Dick). But as Missy and Brat begin falling for each other, she fears their romance may destroy her friendship with Spaz.