Veteran Will Sharp, desperate for money, turns to his adoptive brother Danny for help. A career criminal, Danny instead offers him a huge score. But when their heist goes awry, the desperate brothers hijack an ambulance with a wounded cop and EMT onboard. Will and Danny must evade a city-wide law enforcement response, keep their hostages alive, and somehow try not to kill each other, all while executing the most insane escape LA has ever seen.