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The city's sewer system has been hijacked by a deadly, oversized python, and it's up to an FBI agent (Angel Boris) to track down the only scientist (David Hewlett) who can come up with a way to destroy it. His solution? To unleash on it the wrath of a giant boa constrictor, emboldened by a computer chip implanted in its brain. What ensues is a mad dash to the finish, with the two snakes tearing each other, and everyone else, apart.