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Small-time newsmagazine show host Dr. Steve Brule (John C. Reilly) "checks out" various topics ranging from relationships and fears to local cuisine in this satirical spinoff of Adult Swim's popular "Tim and Eric Awesome Show, Great Job!" The socially inept Brule's segments include an investigation into being pretty or ugly, a conversation about his fear of puppets and an interview with his estranged father, who turns out to be an imposter.