Irene (Vera Farmiga), a drug-addled, working-class mother of two, decides to check herself into a rehab center in upstate New York, where she meets and falls in love with a fellow addict (Hugh Dillon) who's working hard to mend his ways. But when one of them relapses into addiction, can their commitment to each other prevail over the lure of narcotics? Debra Granik won the Director's Award and Farmiga won the Special Jury Prize at Sundance.