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Single mother Luz (Cherry Pie Picache) has her hands full keeping her three sons Oscar (Polo Ravales), Orson (John Prats), and Orwell (Jiro Manio) happy in this Filipino comedy. As Oscar and Orson deal with their homosexuality in different ways, Orwell tries to figure out his own identity. Add a baby and jealous lovers to the mix, and you have the trademark madness of Manay Po. Christian Vasquez co-stars as Luz's boyfriend, Gerry.