Based on the popular manga, this series follows the adventures of two girls named Nana who depend on each other's help to realize their dreams: Nana Komatsu yearns for true love, while Nana Osaki wants to get her punk band off the ground. The two meet on a train to Tokyo, where Nana K. aims to reunite with her boyfriend and Nana O. hopes to make it big in the music business. Despite their differences, the pair hit it off and become roommates.