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Falling into a comatose state after witnessing the murder of her neighbor, Janet Stewart (Anabel Shaw) is suddenly revived by Dr. Richard Cross (Vincent Price) -- the very man responsible for the murder. Unable to convince her husband, Paul (Frank Latimore), that her physician is a cold-blooded killer, Janet must fight for her life inside the walls of a sanitarium with Dr. Cross and his demented nurse and lover (Lynn Bari) in attendance.