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Terrified of passing on the madness that runs in his family, Charlie Kilworth (Christian Campbell) stays away from relationships that could lead to marriage and children. Meanwhile, his grandparents (R.H. Thomson and Wendy Crewson) are debating whether to put his mother (Stockard Channing) into a mental institution. Whoopi Goldberg shares producing credits on this generational drama adapted from the acclaimed novel by Timothy Findley.