When small-time thug Cosimo (Luis Guzman) lands in prison, he learns about a plan for the perfect heist -- but needs someone on the outside to pull it off. Soon, he's contending with a motley crew of screw-ups and losers (including Isaiah Washington, Sam Rockwell and William H. Macy) vying for the job. With the help of a wheelchair-bound safecracker (George Clooney), the team bumbles into misstep after misstep in pursuit of a small fortune.