But Messing will likely always be best known for her breakthrough role as interior designer Grace Adler on the hit sitcom "Will & Grace." The show brought her near-instant stardom and a string of Golden Globe and Emmy nominations; in 2003, she took home the Emmy for Best Actress in a Comedy. In 2007, she earned another Emmy nod for TV's The Starter Wife.
Messing's big-screen credits include A Walk in the Clouds (1995), Hollywood Ending (2002), The Mothman Prophecies (2002), Along Came Polly (2004) and her first leading role in 2005's The Wedding Date (opposite Dermot Mulroney).
When struggling musician Eleanor takes a position as nanny to 12-year-old cello prodigy Reggie, she's thrust into the role of parent, mentor and confidant -- giving rise to a friendship that has profound effects for them both.