Soon after his cross-country move, Roth sold his animated series "Chowdaheads" -- which he co-wrote, directed and produced -- but the show never aired. He found success a few years later, however, when he incorporated his medical maladies into the chilling cult favorite Cabin Fever. Roth's next feature, Hostel (2006), struck box-office gold and spawned a sequel in 2007.
Stepping out from behind the camera, Roth muscled up and took on the supporting role of skull-cracker Donnie Donowitz in 2009's Inglourious Basterds. Roth's subsequent work includes directing and executive-producing the Netflix original series "Hemlock Grove."
Determined to save an Amazon tribe being squeezed by logging, a group of students finds nothing but trouble when their plane crashes in the jungle. Soon, the activists are on the menu of the folks they came to save in this unnerving cannibal fest.