Parsons got his career start with a 2002 guest appearance on "Ed" and then shifted gears to feature films with a small but memorable part in director Zach Braff's Garden State (2004), among other projects. A recurring role on "Judging Amy" followed, but Parsons wouldn't hit the big time, critically speaking, until joining the "Big Bang" cast, playing opposite Johnny Galecki in a priceless odd-couple pairing that garnered Parsons an Emmy in 2010 and a Golden Globe Award the next year.
Other screen credits on the actor's résumé include the zany 2006 comedy School for Scoundrels.
Quarks fly when ultra-geeky Caltech physicists Sheldon and Leonard (Jim Parsons and Johnny Galecki) discover that they have a new neighbor: Penny (Kaley Cuoco), a sexy actress who inspires the lads to try a relationship with something other than their particle accelerators. This science-savvy hit sitcom co-stars Simon Helberg and Kunal Nayyar as friends and fellow nerds who reveal they also have a thing or two to learn about the fairer sex.